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- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2025
Uryu K, Zhao X, Shiozaki M, Yu Z.
2025. Cryo-electron Microscopy of Vitreous Sections (CEMOVIS) Application for Model Organisms. Microscopy and Microanalysis. 31(1(Supp)):ozaf048.484.
Hou K, Ge P, Sawaya MR, Lutter L, Dolinsky JL, Yang Y, Jiang YXiao, Boyer DR, Cheng X, Pi J et al..
2025. How short peptides disassemble tau fibrils in Alzheimer's disease. Nature.
Rosenthal JS, Zhang D, Yin J, Long C, Yang G, Li Y, Lu Z, Li W-P, Yu Z, Li J et al..
2025. Molecular organization of central cholinergic synapses.. Proc Natl Acad Sci U S A. 122(17):e2422173122.
Zhang Z, Feng Z, Zhao X, Yu Z, Chapman ER.
2025. Programmable Liposome Organization via DNA Origami Templates.. J Am Chem Soc.
Zhang Z, Feng Z, Zhao X, Yu Z, Chapman ER.
2025. Programmable Liposome Organization via DNA Origami Templates.. J Am Chem Soc. 147(28):24548-24554.
Zhou H, Hutchings J, Shiozaki M, Zhao X, Doolittle LK, Yang S, Yan R, Jean N, Riggi M, Yu Z et al..
2025. Quantitative spatial analysis of chromatin biomolecular condensates using cryoelectron tomography.. Proc Natl Acad Sci U S A. 122(19):e2426449122.
2024
Ackerman D, Avetissian E, Bleck CKE, Bogovic JA, Innerberger M, Korff W, Li W-P, Lu Z, Petruncio A, Preibisch S et al..
2024. Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning. bioRxiv.
Hou K, Ge P, Sawaya MR, Dolinsky JL, Yang Y, Jiang YXiao, Lutter L, Boyer D, Cheng X, Pi J et al..
2024. How short peptides can disassemble ultra‐stable tau fibrils extracted from Alzheimer’s disease brain by a strain‐relief mechanism. Alzheimer's & Dementia. 20(S6)
Zhou H, Hutchings J, Shiozaki M, Zhao X, Doolittle LK, Yang S, Yan R, Jean N, Riggi M, Yu Z et al..
2024. Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography. bioRxiv.
2023
Zhang Z, Feng Z, Zhao X, Jean D, Yu Z, Chapman ER.
2023. Functionalization and higher-order organization of liposomes with DNA nanostructures.. Nature Communications. 14(1):5256.
Wright KM, DiNapoli SR, Miller MS, P Azurmendi A, Zhao X, Yu Z, Chakrabarti M, Shi WX, Douglass J, Hwang MS et al..
2023. Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.. Nature Communications. 14(1):5063.
Chen Z, Greenan GA, Shiozaki M, Liu Y, Skinner WM, Zhao X, Zhao S, Yan R, Yu Z, Lishko PV et al..
2023. In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes.. Nature Structural & Molecular Biology. 30(3):360-9.
2022
Wasmuth EV, Broeck AVanden, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W et al..
2022. Allosteric interactions prime androgen receptor dimerization and activation.. Molecular Cell. 82(11):2021-31.
Shaban NM, Yan R, Shi K, Moraes SN, Cheng AZ, Carpenter MA, McLellan JS, Yu Z, Harris RS.
2022. Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.. Science Advances. 8(17):eabm2827.
Egri SB, Ouch C, Chou H-T, Yu Z, Song K, Xu C, Shen K.
2022. Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.. Molecular Cell. 36(1)
Hirano S, Kappel K, Altae-Tran H, Faure G, Wilkinson ME, Kannan S, F Demircioglu E, Yan R, Shiozaki M, Yu Z et al..
2022. Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA.. Nature. 610(7932):575-581.
2021
Caveney NA, Workman SD, Yan R, Atkinson CE, Yu Z, Strynadka NCJ.
2021. CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution.. Nature Communications. 12(1):2775.
Qiu B, Matthies D, Fortea E, Yu Z, Boudker O.
2021. Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport.. Sciences Advances. 7(10)
Fukudome A, Singh J, Mishra V, Reddem E, Martinez-Marquez F, Wenzel S, Yan R, Shiozaki M, Yu Z, Wang JChe-Yen et al..
2021. Structure and RNA template requirements of RNA-DEPENDENT RNA POLYMERASE 2.. Proceedings of the National Academy of Sciences of the U.S.A.. 118(51)
2020
Matthies D, Lee NYJ, Gatera I, H Pasolli A, Zhao X, Liu H, Walpita D, Liu Z, Yu Z, Ioannou MS.
2020. Microdomains form on the luminal face of neuronal extracellular vesicle membranes.. Scientific Reports. 10(1):11953.
He S, Chou H-T, Matthies D, Wunder T, Meyer MT, Atkinson N, Martinez-Sanchez A, Jeffrey PD, Port SA, Patena W et al..
2020. The structural basis of Rubisco phase separation in the pyrenoid.. Nature Plants.
He S, Chou H-T, Matthies D, Wunder T, Meyer MT, Atkinson N, Martinez-Sanchez A, Jeffrey PD, Port SA, Patena W et al..
2020. The structural basis of Rubisco phase separation in the pyrenoid.. Nature Plants. 6(12):1480-1490.
2019
Majewski DD, Worrall LJ, Hong C, Atkinson CE, Vuckovic M, Watanabe N, Yu Z, Strynadka NCJ.
2019. Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.. Nature Communications. 10(1):626.
Shen K, Rogala KB, Chou H-T, Huang RK, Yu Z, Sabatini DM.
2019. Cryo-EM structure of the human FLCN-FNIP2-Rag-Ragulator complex.. Cell. 179(6):1319-29.