Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning

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bioRxiv. 2024 Sep 07;. doi: 10.1101/2024.09.05.611438

Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning CellMapScientific Computing

Ackerman D, Avetissian E, Bleck CK, Bogovic JA, Innerberger M, Korff W, Li W, Lu Z, Petruncio A, Preibisch S, Qiu W, Rhoades Jeff, Saalfeld S, Silva M, Trautman ET, Vorimo R, Weigel A, Yu Z, Zubov Y,

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Abstract

This report presents a comprehensive data release exploring the tissue microarchitecture of P7 aged mice using Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) combined with machine learning-based segmentations of nuclei. The study includes high-resolution 3D volumes and nucleus segmentations for seven vital tissues—pancreas, liver, kidney, heart, thymus, hippocampus, and skin—from a single mouse. The detailed datasets are openly accessible on OpenOrganelle.org, providing a valuable resource for the scientific community to support further research and collaboration.

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