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Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2016
2015
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH et al..
2015. A general method to improve fluorophores for live-cell and single-molecule microscopy.. Nature Methods. 12(3):244-50.
Liu Z, Lavis LD, Betzig E.
2015. Imaging live-cell dynamics and structure at the single-molecule level.. Molecular Cell. 58(4):644-59.
Lester HA, Lavis LD, Dougherty DA.
2015. Ketamine Inside Neurons? American Journal of Psychiatry. 172(11):1064-6.
R. Johnson J, Hoops GC, Savas CJ, Kartje Z, Lavis LD.
2015. A sensitive and robust enzyme kinetic experiment using microplates and fluorogenic ester substrates. Journal of Chemical Education. 92(2):385-8.
Grimm JB, Klein T, Kopek BG, Shtengel G, Hess HF, Sauer M, Lavis LD.
2015. Synthesis of a far-red photoactivatable silicon-containing rhodamine for super-resolution microscopy.. Angewandte Chemie (International ed. in English). 55(5):1723-7.
2014
Liu Z, Legant WR, Chen B-C, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R.
2014. 3D imaging of Sox2 enhancer clusters in embryonic stem cells.. eLife. 3
Lavis LD, Raines RT.
2014. Bright building blocks for chemical biology.. ACS Chemical Biology. 9(4):855-66.
Lukowski JK, Savas CP, Gehring AM, McKary MG, Adkins CT, Lavis LD, Hoops GC, R Johnson J.
2014. Distinct substrate selectivity of a metabolic hydrolase from Mycobacterium tuberculosis.. Biochemistry. 53(47):7386-95.
Mast JD, De Moraes CM, Alborn HT, Lavis LD, Stern DL.
2014. Evolved differences in larval social behavior mediated by novel pheromones.. eLife. 3
Haga-Yamanaka S, Ma L, He J, Qiu Q, Lavis LD, Looger LL, C Yu R.
2014. Integrated action of pheromone signals in promoting courtship behavior in male mice.. eLife. 3:e03025.
Höckendorf B, Lavis LD, Keller PJ.
2014. Making biology transparent.. Nature Biotechnology. 32(11):1104-5.
Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R.
2014. Single-molecule tracking of the transcription cycle by sub-second RNA detection.. eLife. 3:e01775.
2013
Banghart MR, Williams JT, Shah RC, Lavis LD, Sabatini BL.
2013. Caged naloxone reveals opioid signaling deactivation kinetics.. Molecular Pharmacology. 84(5):687-95.
Grimm JB, Sung AJ, Legant WR, Hulamm P, Matlosz SM, Betzig E, Lavis LD.
2013. Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes.. ACS Chemical Biology. 8(6):1303-10.
Grimm JB, Heckman LM, Lavis LD.
2013. The chemistry of small-molecule fluorogenic probes.. Progress in Molecular Biology and Translational Science. 113:1-34.
Ellis EE, Adkins CT, Galovska NM, Lavis LD, R Johnson J.
2013. Decoupled roles for the atypical, bifurcated binding pocket of the ybfF hydrolase.. Chembiochem : A European Journal of Chemical Biology. 14(9):1134-44.
Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I, Shuvalova L et al..
2013. Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.. J Biol Chem. 288(15):10522-35.
2012
Mütze J, Iyer V, Macklin JJ, Colonell J, Karsh B, sek Z\vek Petrá\, Schwille P, Looger LL, Lavis LD, Harris TD.
2012. Excitation spectra and brightness optimization of two-photon excited probes.. Biophysical Journal. 102(4):934-44.
Tian L, Yang Y, Wysocki LM, Arnold AC, Hu A, Ravichandran B, Sternson SM, Looger LL, Lavis LD.
2012. Selective esterase-ester pair for targeting small molecules with cellular specificity.. Proceedings of the National Academy of Sciences of the United States of America. 109:4756-61.
Hedge MK, Gehring AM, Adkins CT, Weston LA, Lavis LD, R Johnson J.
2012. The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima.. Biochimica et Biophysica Acta. 1824(9):1024-30.
2011
Wysocki LM, Lavis LD.
2011. Advances in the chemistry of small molecule fluorescent probes.. Current Opinion in Chemical Biology. 15(6):752-9.
Wysocki LM, Grimm JB, Tkachuk AN, Brown TA, Betzig E, Lavis LD.
2011. Facile and general synthesis of photoactivatable xanthene dyes.. Angewandte Chemie. 50:11206-9.
Lavis LD.
2011. Histochemistry: live and in color.. The Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society. 59:139-45.