Biblio

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2016
Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z.  2016.  Real-time imaging of Huntingtin aggregates diverting target search and gene transcription.. eLife. 5
Morisaki T, Lyon K, DeLuca KF, DeLuca JG, English BP, Zhang Z, Lavis LD, Grimm JB, Viswanathan S, Looger LL.  2016.  Real-time quantification of single RNA translation dynamics in living cells.. Science. 352(6292):1425-9.
Cho W-K, Jayanth N, English BP, Inoue T, J Andrews O, Conway W, Grimm JB, Spille J-H, Lavis LD, Lionnet T et al..  2016.  RNA Polymerase II cluster dynamics predict mRNA output in living cells.. eLife. 5
Swinstead EE, Miranda TB, Paakinaho V, Baek S, Goldstein I, Hawkins M, Karpova TS, Ball D, Mazza D, Lavis LD et al..  2016.  Steroid receptors reprogram FoxA1 occupancy through dynamic chromatin transitions.. Cell.
Grimm JB, Gruber TD, Ortiz G, Brown TA, Lavis LD.  2016.  Virginia Orange: A versatile, red-shifted fluorescein scaffold for single- and dual-input fluorogenic probes.. Bioconjugate Chemistry. 27(2):474-80.
2015
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH et al..  2015.  A general method to improve fluorophores for live-cell and single-molecule microscopy.. Nature Methods. 12(3):244-50.
Liu Z, Lavis LD, Betzig E.  2015.  Imaging live-cell dynamics and structure at the single-molecule level.. Molecular Cell. 58(4):644-59.
Lester HA, Lavis LD, Dougherty DA.  2015.  Ketamine Inside Neurons? American Journal of Psychiatry. 172(11):1064-6.
R. Johnson J, Hoops GC, Savas CJ, Kartje Z, Lavis LD.  2015.  A sensitive and robust enzyme kinetic experiment using microplates and fluorogenic ester substrates. Journal of Chemical Education. 92(2):385-8.
Grimm JB, Klein T, Kopek BG, Shtengel G, Hess HF, Sauer M, Lavis LD.  2015.  Synthesis of a far-red photoactivatable silicon-containing rhodamine for super-resolution microscopy.. Angewandte Chemie (International ed. in English). 55(5):1723-7.
2014
Liu Z, Legant WR, Chen B-C, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R.  2014.  3D imaging of Sox2 enhancer clusters in embryonic stem cells.. eLife. 3
Lavis LD, Raines RT.  2014.  Bright building blocks for chemical biology.. ACS Chemical Biology. 9(4):855-66.
Lukowski JK, Savas CP, Gehring AM, McKary MG, Adkins CT, Lavis LD, Hoops GC, R Johnson J.  2014.  Distinct substrate selectivity of a metabolic hydrolase from Mycobacterium tuberculosis.. Biochemistry. 53(47):7386-95.
Mast JD, De Moraes CM, Alborn HT, Lavis LD, Stern DL.  2014.  Evolved differences in larval social behavior mediated by novel pheromones.. eLife. 3
Haga-Yamanaka S, Ma L, He J, Qiu Q, Lavis LD, Looger LL, C Yu R.  2014.  Integrated action of pheromone signals in promoting courtship behavior in male mice.. eLife. 3:e03025.
Höckendorf B, Lavis LD, Keller PJ.  2014.  Making biology transparent.. Nature Biotechnology. 32(11):1104-5.
Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R.  2014.  Single-molecule tracking of the transcription cycle by sub-second RNA detection.. eLife. 3:e01775.
2013
Banghart MR, Williams JT, Shah RC, Lavis LD, Sabatini BL.  2013.  Caged naloxone reveals opioid signaling deactivation kinetics.. Molecular Pharmacology. 84(5):687-95.
Grimm JB, Sung AJ, Legant WR, Hulamm P, Matlosz SM, Betzig E, Lavis LD.  2013.  Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes.. ACS Chemical Biology. 8(6):1303-10.
Grimm JB, Heckman LM, Lavis LD.  2013.  The chemistry of small-molecule fluorogenic probes.. Progress in Molecular Biology and Translational Science. 113:1-34.
Ellis EE, Adkins CT, Galovska NM, Lavis LD, R Johnson J.  2013.  Decoupled roles for the atypical, bifurcated binding pocket of the ybfF hydrolase.. Chembiochem : A European Journal of Chemical Biology. 14(9):1134-44.
Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I, Shuvalova L et al..  2013.  Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.. J Biol Chem. 288(15):10522-35.
2012
Mütze J, Iyer V, Macklin JJ, Colonell J, Karsh B, sek Z\vek Petrá\, Schwille P, Looger LL, Lavis LD, Harris TD.  2012.  Excitation spectra and brightness optimization of two-photon excited probes.. Biophysical Journal. 102(4):934-44.
Tian L, Yang Y, Wysocki LM, Arnold AC, Hu A, Ravichandran B, Sternson SM, Looger LL, Lavis LD.  2012.  Selective esterase-ester pair for targeting small molecules with cellular specificity.. Proceedings of the National Academy of Sciences of the United States of America. 109:4756-61.
Hedge MK, Gehring AM, Adkins CT, Weston LA, Lavis LD, R Johnson J.  2012.  The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima.. Biochimica et Biophysica Acta. 1824(9):1024-30.