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9 Results

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    Biotin-Janelia Fluor® Conjugates
    Overview  Biotin-Janelia Fluor® conjugates are cell-permeable, fluorescent ligands designed for dual-purpose applications: live-cell imaging and biochemical purification using the HaloTag...
    Tools
    Bright and Targetable Red Ca²⁺ Indicators "JF-BAPTA"
    Overview JF-BAPTA indicators merge the fluorescence power of Janelia Fluor dyes with the Ca²⁺ sensitivity of BAPTA and the genetic targeting precision of HaloTag. This next-generation sensor...
    Tools
    Bright, Photoactivatable Janelia Fluor Dyes for Super-Resolution Imaging
    Overview Photoactivatable (PA) Janelia Fluor dyes combine small-molecule fluorophores' superior brightness, photostability, and cell permeability with precise light-controlled activation. By...
    Tools
    HaloCaMP: Chemigenetic Calcium Indicators Using HaloTag and Janelia Fluor Dyes
    Overview HaloCaMP integrates circularly permuted HaloTag proteins with a range of Janelia Fluor (JF) dyes to form...
    Tools
    Janelia Fluor® Dyes
    Bright and photostable fluorescent labels are critical tools for the life sciences.  A key determinant of fluorophore performance is the quantum yield (QY); dyes with improved QY values are...
    Tools
    JFX Dyes
    The Janelia Fluor® dyes, developed by the Lavis Lab at Janelia Research Campus, outperform other fluorophores in brightness and photostability, enabling new experiments at the frontier of life...
    Tools
    Photochromic and Spontaneously Blinking Janelia Fluor Dyes
    Overview A versatile platform enabling the rational design of super-resolution imaging dyes by amide-coupling rhodamines to coumarin auxiliaries. Depending on the rhodamine’s lactone–zwitterion...
    Tools
    Red-Shifted and Fluorinated Dyes "JF3" for Advanced Bioimaging
    Overview Fluorination and structural tuning of rhodamine scaffolds have yielded a powerful new class of bright, red-shifted fluorescent dyes for live-cell and super-resolution microscopy....
    Tools
    Vibratome built for the Auto Slicer Imager Rig (MouseLight 2)
    About the Innovation Visualization of the axonal structures of individual neurons is critical to understand how neural signals are organized and communicated in the brain. Janelia...