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Magneto-Caloric Materials for MRI

Submitted by custardj on Wed, 2019-08-14 10:02

This technology is a non-gadolinium-based contrast material for use in MRI (magnetic resonance imaging) scans. Contrast material is injected into the patient to help visualize physiological structures and support the interpretation of images. Contrast materials in use today are only weakly influenced by magnetic and temperature changes in typical MRI magnetic fields. This novel contrast material is magneto-caloric, susceptible to sharp phase change at a range of direct current (DC) magnetic field values around physiological relevant temperatures.

CASFISH: DNA labeling with CRISPR/Cas9

perhamm's picture
Submitted by perhamm on Fri, 2016-06-03 17:04

Genomic DNA in cells is highly folded and organized in three dimensions. Detection and visualization of genomic DNA are widely accomplished by using various fluorescence in situ hybridization (FISH) methods. However, despite enhancements to DNA FISH methods, the use of chemicals or heat in the process results in denaturation of the DNA and potentially affects the integrity of the biological structure, which limits research related to the understanding of gene expression.