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- Cryo-Electron Microscopy
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janelia7_blocks-janelia7_biblio_header | block
Current Opinion in Neurobiology. 2022 Mar 11;73:102523. doi: 10.1016/j.conb.2022.02.003
Context-dependent control of behavior in Drosophila. Card Lab
Oram TB, Card GM
janelia7_blocks-janelia7_biblio_abstract | block
Abstract
The representation of contextual information peripheral to a salient stimulus is central to an animal's ability to correctly interpret and flexibly respond to that stimulus. While the computations and circuits underlying the context-dependent modulation of stimulus-response pairings have typically been studied in vertebrates, the genetic tractability, numeric simplification, and well-characterized connectivity patterns of the Drosophila melanogaster brain have facilitated circuit-level insights into contextual processing. Recent studies in flies reveal the neuronal mechanisms that create flexible context-dependent behavioral responses to sensory events in conditions of predation threat, feeding regulation, and social interaction.