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5017 Results

Showing 4911-4920 of 5017 results
People
Wei Wu
Research Specialist
People
Wei-Ping Li
Research Specialist
People
Weixing Pan
Senior Scientist
People
Weiyu Chen
Postdoctoral Scientist 05
Tools
WHaloCaMP: Modular, Bright, and Multiplexable Chemigenetic Calcium Indicators
Conferences
What Can Computer Vision Do for Neuroscience and Vice Versa?
Participants at this conference will consider current challenges and recent progress in computer vision and image analysis techniques that may advance neuroscience studies. We will explore such...
Conferences
What Can Computer Vision Do for Neuroscience and Vice Versa? 2010
This conference was a follow-up to the first one, held in 2008. We considered current challenges and recent advances in computer vision and image analysis techniques that may advance neuroscience...
Publications
05/05/17 | What can tiny mushrooms in fruit flies tell us about learning and memory?
Hige T
Neuroscience Research. 2017 May 05;129:8-16. doi: 10.1016/j.neures.2017.05.002

Nervous systems have evolved to translate external stimuli into appropriate behavioral responses. In an ever-changing environment, flexible adjustment of behavioral choice by experience-dependent learning is essential for the animal's survival. Associative learning is a simple form of learning that is widely observed from worms to humans. To understand the whole process of learning, we need to know how sensory information is represented and transformed in the brain, how it is changed by experience, and how the changes are reflected on motor output. To tackle these questions, studying numerically simple invertebrate nervous systems has a great advantage. In this review, I will feature the Pavlovian olfactory learning in the fruit fly, Drosophila melanogaster. The mushroom body is a key brain area for the olfactory learning in this organism. Recently, comprehensive anatomical information and the genetic tool sets were made available for the mushroom body circuit. This greatly accelerated the physiological understanding of the learning process. One of the key findings was dopamine-induced long-term synaptic plasticity that can alter the representations of stimulus valence. I will mostly focus on the new studies within these few years and discuss what we can possibly learn about the vertebrate systems from this model organism.

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Science News
12/18/17 | What is Mechanistic Cognitive Neuroscience: Q&A with Vivek Jayaraman
What is Neuronal Cell Biology?