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Expansion Microscopy and mFISH technology development
I received my PhD in developmental biology from the ICRF/UCL, under Julian Lewis examining the role of Notch signaling chick inner ear development. I completed my post-doctoral training under Ulrike Heberlein at UCSF. Here I discovered that synapse number is a mechanism that regulates alcohol sensitivity in flies. This study lead me to my interest in the genetic regulation of the effects of social isolation (aggression, activity and alcohol resistance) which I pursued as a staff scientist in the Heberlein Lab at Janelia in 2013. In 2017, I joined the Project Technical Resource team. Here, I principally work with Paul Tillberg and Scott Sternson on developing technology to visualize RNA expression, at the level of single molecules, of up to 50 different genes in the same piece of expanded tissue.