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janelia7_blocks-janelia7_biblio_header | block
Cell Metabolism. 2012 Feb 8;15(2):133-4. doi: 10.1016/j.cmet.2012.01.011
Neuron transplantation partially reverses an obesity disorder in mice. Sternson Lab

Sternson SM
janelia7_blocks-janelia7_biblio_abstract | block
Abstract
Mice lacking leptin receptors are grossly obese and diabetic, in part due to dysfunction in brain circuits important for energy homeostasis. Transplantation of leptin receptor-expressing hypothalamic progenitor neurons into the brains of leptin receptor deficient mice led to integration into neural circuits, reduced obesity, and normalized circulating glucose levels.
PMID: 22326215 [PubMed - indexed for MEDLINE]
node:body | entity_field