Pupil-segmentation-based adaptive optical microscopy with full-pupil illumination.

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Optics Letters. 2011 Nov 1;36(21):4206-8. doi: 10.1364/OL.36.004206

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Pupil-segmentation-based adaptive optical microscopy with full-pupil illumination. Betzig LabJi Lab

Milkie DE, Betzig E, Ji N

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Abstract

Optical aberrations deteriorate the performance of microscopes. Adaptive optics can be used to improve imaging performance via wavefront shaping. Here, we demonstrate a pupil-segmentation based adaptive optical approach with full-pupil illumination. When implemented in a two-photon fluorescence microscope, it recovers diffraction-limited performance and improves imaging signal and resolution.

PMID: 22048366 [PubMed - indexed for MEDLINE]

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Pupil-segmentation-based adaptive optical microscopy with full-pupil illumination.

Abstract

PMID: 22048366 [PubMed - indexed for MEDLINE]

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