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Filters: Author is Gonen, Tamir  [Clear All Filters]
2023
Nguyen C, Lei H-T, Lai LTung Faat, Gallenito MJ, Mu X, Matthies D, Gonen T.  2023.  Lipid flipping in the omega-3 fatty-acid transporter.. Nature Communications. 14(1):2571.
2019
M de la Cruz J, Martynowycz MW, Hattne J, Gonen T.  2019.  MicroED data collection with SerialEM.. Ultramicroscopy. 201:77-80.
Ma J, Lei H-T, Reyes FE, Sanchez-Martinez S, Sarhan MF, Hattne J, Gonen T.  2019.  Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS.. Proceedings of the National Academy of Sciences of the United States of America. 116(6):2086-90.
2018
Hattne J, Shi D, Glynn C, Zee C-T, Gallagher-Jones M, Martynowycz MW, Rodriguez JA, Gonen T.  2018.  Analysis of global and site-specific radiation damage in cryo-EM.. Structure (London, England : 1993). 26(5):759-66.
Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Z Zhou H, Eisenberg DS.  2018.  Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.. Nature Structural & Molecular Biology.
Lei H-T, Ma J, Martinez SSanchez, Gonen T.  2018.  Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state.. Nature Structural & Molecular Biology. 25(6):522-527.
Martynowycz MW, Gonen T.  2018.  From electron crystallography of 2D crystals to MicroED of 3D crystals.. Current Opinion in Colloid & Interface Science . 34:9-16.
Liu S, Gonen T.  2018.  MicroED structure of the NaK ion channel reveals a Na partition process into the selectivity filter.. Communications Biology. 1:38.
Purdy MD, Shi D, Chrustowicz J, Hattne J, Gonen T, Yeager M.  2018.  MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat.. Proceedings of the National Academy of Sciences of the United States of America. 115(52):13258-63.
Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee C-T, Novikova IV, Goldschmidt L, McFarlane HT et al..  2018.  Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp.. Nature Structural & Molecular Biology.
2017
Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S et al..  2017.  Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity.. eLife. 6
M de la Cruz J, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SKyung et al..  2017.  Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.. Nature Methods. 14(4):399-402.
Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J et al..  2017.  Common fibrillar spines of amyloid-β and human Islet Amyloid Polypeptide revealed by Micro Electron Diffraction and inhibitors developed using structure-based design.. The Journal of Biological Chemistry. 293(8):2888-902.
Hughes MP, Sawaya MR, Goldschmidt L, Rodriguez JA, Cascio D, Gonen T, Eisenberg DS.  2017.  Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets.. bioRxiv.
de la Cruz MJason, Martynowycz M, Hattne J, Shi D, Gonen T.  2017.  A method to minimize condenser lens-induced hysteresis effects in a JEOL JEM-3200FSC microscope to enable stable cryoEM low-dose operations.. bioRxiv.
Vergara S, Lukes DA, Martynowycz MW, Santiago U, Plascencia-Villa G, Weiss SC, de la Cruz MJason, Black DM, Alvarez MM, Lopez-Lozano X et al..  2017.  MicroED structure of Au146(p-MBA)57 at subatomic resolution reveals a twinned FCC cluster.. Journal of Physical Chemistry Letters. 8(5523-30):arXiv:1706.07902[physics.atm-clus].
Martynowycz M, Glynn C, Miao J, de la Cruz MJason, Hattne J, Shi D, Cascio D, Rodriguez J, Gonen T.  2017.  MicroED structures from micrometer thick protein crystals.. bioRxiv.
Wright ZVF, McCarthy S, Dickman R, Reyes FE, Sanchez-Martinez S, Cryar A, Kilford I, Hall A, Takle AK, Topf M et al..  2017.  The role of disulfide bond replacements in analogues of the tarantula toxin ProTx-II and their effects on inhibition of the voltage-gated sodium ion channel Nav1.7.. Journal of the American Chemical Society. 139(37):13063-75.
Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS.  2017.  Structure-based inhibitors of tau aggregation.. Nature Chemistry.
Rodriguez JA, Eisenberg DS, Gonen T.  2017.  Taking the measure of MicroED.. Current Opinion in Structural Biology. 46:79-86.
2016
Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS.  2016.  Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.. Proceedings of the National Academy of Sciences of the United States of America. 113(40):11232-6.
Bale JB, Gonen S, Liu Y, Sheffler W, Ellis D, Thomas C, Cascio D, Yeates TO, Gonen T, King NP et al..  2016.  Accurate design of megadalton-scale two-component icosahedral protein complexes.. Science (New York, N.Y.). 353(6297):389-94.
Shi D, Nannenga BL, M de la Cruz J, Liu J, Sawtelle S, Calero G, Reyes FE, Hattne J, Gonen T.  2016.  The collection of MicroED data for macromolecular crystallography.. Nature Protocols. 11(5):895-904.
Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D et al..  2016.  Data publication with the structural biology data grid supports live analysis.. Nature Communications. 7:10882.
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang P-S, Ravichandran R et al..  2016.  Design of a hyperstable 60-subunit protein icosahedron.. Nature.