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    Espinosa Medina Lab
    12/01/19 | High-throughput dense reconstruction of cell lineages.
    Isabel Espinosa Medina , Garcia-Marques J, Cepko C, Lee T
    Open Biology. 2019 Dec 01;9(12):190229. doi: 10.1098/rsob.190229

    The first meeting exclusively dedicated to the 'High-throughput dense reconstruction of cell lineages' took place at Janelia Research Campus (Howard Hughes Medical Institute) from 14 to 18 April 2019. Organized by Tzumin Lee, Connie Cepko, Jorge Garcia-Marques and Isabel Espinosa-Medina, this meeting echoed the recent eruption of new tools that allow the reconstruction of lineages based on the phylogenetic analysis of DNA mutations induced during development. Combined with single-cell RNA sequencing, these tools promise to solve the lineage of complex model organisms at single-cell resolution. Here, we compile the conference consensus on the technological and computational challenges emerging from the use of the new strategies, as well as potential solutions.

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