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2 Publications

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    Pavlopoulos Lab
    01/01/07 | Hox go omics: insights from Drosophila into Hox gene targets.
    Pavlopoulos A, Akam M
    Genome Biology. 2007;8(3):208. doi: 10.1186/gb-2007-8-3-208

    Genetic studies of the targets of the Hox genes have revealed only the tip of the iceberg. Recent microarray studies that have identified hundreds more transcriptional responses to Hox genes in Drosophila will help elucidate the role of Hox genes in development and evolution.

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    Pavlopoulos Lab
    10/31/07 | The DNA transposon Minos as a tool for transgenesis and functional genomic analysis in vertebrates and invertebrates.
    Pavlopoulos A, Oehler S, Kapetanaki MG, Savakis C
    Genome Biology. 2007 Oct 31;8 Suppl 1:S2. doi: 10.1186/gb-2007-8-s1-s2

    Transposons are powerful tools for conducting genetic manipulation and functional studies in organisms that are of scientific, economic, or medical interest. Minos, a member of the Tc1/mariner family of DNA transposons, exhibits a low insertional bias and transposes with high frequency in vertebrates and invertebrates. Its use as a tool for transgenesis and genome analysis of rather different animal species is described.

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