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1 Janelia Publications
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Eddy/Rivas Lab
12/07/11 |
Phosphorylation at the interface.
Structure . 2011 Dec 7;19:1726-7. doi: 10.1016/j.str.2011.11.006
Proteomic studies have identified thousands of eukaryotic phosphorylation sites (phosphosites), but few are functionally characterized. Nishi et al., in this issue of Structure, characterize phosphosites at protein-protein interfaces and estimate the effect of their phosphorylation on interaction affinity, by combining proteomics data with protein structures.