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Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Fly Facility
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
Book Chapter
Kreshuk A, Funke J, Cardona A, Hamprecht FA.
2015. Who is talking to whom: Synaptic partner detection in anisotropic volumes of insect brain.. Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2015. :661-8.
Conference Paper
Funke J, Andres B, Hamprecht F, Cardona A, Cook M.
2012. Efficient automatic 3D-reconstruction of branching neurons from EM data.. Computer Vision and Pattern Recognition (CVPR), 2012 IEEE Conference on.
Tschopp F, Martel JNP, Turaga SC, Cook M, Funke J.
2016. Efficient convolutional neural networks for pixelwise classification on heterogeneous hardware systems.. IEEE 13th International Symposium on Biomedical Imaging: From Nano to Macro.
Wolf S, Hamprecht FA, Funke J.
2020. Inpainting Networks Learn to Separate Cells in Microscopy Images. British Machine Vision Conference.
Journal Article
Plaza SM, Funke J.
2018. Analyzing image segmentation for connectomics.. Frontiers in Neural Circuits. 12:102.
Malin-Mayor C, Hirsch P, Guignard L, McDole K, Wan Y, Lemon WC, Kainmueller D, Keller PJ, Preibisch S, Funke J.
2023. Automated reconstruction of whole-embryo cell lineages by learning from sparse annotations.. Nature Biotechnology. 41(1):44-49.
Malin-Mayor C, Hirsch P, Guignard L, McDole K, Wan Y, Lemon WC, Kainmueller D, Keller PJ, Preibisch S, Funke J.
2022. Automated reconstruction of whole-embryo cell lineages by learning from sparse annotations.. Nature Biotechnology.
Buhmann J, Sheridan A, Gerhard S, Krause R, Nguyen T, Heinrich L, Schlegel P, Lee W-CAllen, Wilson R, Saalfeld S et al..
2021. Automatic Detection of Synaptic Partners in a Whole-Brain Drosophila EM Dataset. Nature Methods. 18(7):771-4.
Funke J, Zhang C, Pietzsch T, Ballester MAGonzalez, Saalfeld S.
2017. The candidate multi-cut for cell segmentation.. 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018).
Kuan AT, Phelps JS, Thomas LA, Nguyen TM, Han J, Chen C-L, Azevedo AW, Tuthill JC, Funke J, Cloetens P et al..
2020. Dense neuronal reconstruction through X-ray holographic nano-tomography.. Nature Neuroscience. 23(12):1637-43.
Funke J, Tschopp FD, Grisaitis W, Sheridan A, Singh C, Saalfeld S, Turaga SC.
2019. Large scale image segmentation with structured loss based deep learning for connectome reconstruction.. IEEE Transactions on Pattern Analysis and Machine Intelligence. 41(7):1669-80.
Sheridan A, Nguyen TM, Deb D, Lee W-CAllen, Saalfeld S, Turaga SC, Manor U, Funke J.
2023. Local shape descriptors for neuron segmentation.. Nature Methods. 20(2):295-303.
Sheridan A, Nguyen T, Deb D, Lee W-CAllen, Saalfeld S, Turaga S, Manor U, Funke J.
2021. Local Shape Descriptors for Neuron Segmentation. bioRxiv.
Baker CA, McKellar C, Pang R, Nern A, Dorkenwald S, Pacheco DA, Eckstein N, Funke J, Dickson BJ, Murthy M.
2022. Neural network organization for courtship-song feature detection in Drosophila.. Current Biology. 32(15):3317-3333.e7.
Dorkenwald S, Matsliah A, Sterling AR, Schlegel P, Yu S-C, McKellar CE, Lin A, Costa M, Eichler K, Yin Y et al..
2023. Neuronal wiring diagram of an adult brain.. bioRxiv.
Eckstein N, Bates AShakeel, Champion A, Du M, Yin Y, Schlegel P, Lu AKun-Yang, Rymer T, Finley-May S, Paterson T et al..
2024. Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster. Cell. 187(10):2574-2594.e23.
Maniates-Selvin JT, Hildebrand DGrant Colb, Graham BJ, Kuan AT, Thomas LA, Nguyen T, Buhmann J, Azevedo AW, Shanny BL, Funke J et al..
2021. Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy. Cell. 184(3)
Nguyen TM, Thomas LA, Rhoades JL, Ricchi I, Yuan XCindy, Sheridan A, Hildebrand DGC, Funke J, Regehr WG, Lee W-CAllen.
2023. Structured cerebellar connectivity supports resilient pattern separation.. Nature. 613(7944):543-549.
Funke J, Klein J, Moreno-Noguer F, Cardona A, Cook M.
2016. Structured learning of assignment models for neuron reconstruction to minimize topological errors.. IEEE 13th International Symposium on Biomedical Imaging (ISBI). :607-11.
Heinrich L, Funke J, Pape C, Nunez-Iglesias J, Saalfeld S.
2018. Synaptic cleft segmentation in non-isotropic volume electron microscopy of the complete Drosophila brain.. Medical Image Computing and Computer Assisted Intervention – MICCAI 2018. :317-25.
Buhmann J, Krause R, Lentini RCeballos, Eckstein N, Cook M, Turaga SC, Funke J.
2018. Synaptic partner prediction from point annotations in insect brains.. MICCAI 2018: Medical Image Computing and Computer Assisted Intervention.
Funke J, Klein J, Moreno-Noguer F, Cardona A, Cook M.
2017. TED: A Tolerant Edit Distance for segmentation evaluation.. Methods. 115:119-27.
Heinrich L, Patton W, Bennett D, Ackerman D, Park G, Bogovic JA, Eckstein N, Petruncio A, Clements J, Pang S et al..
2023. Towards Generalizable Organelle Segmentation in Volume Electron Microscopy.. Microscopy and Microanalysis. 29(Supplement_1):975.
Zhu P-P, Hung H-F, Batchenkova N, Nixon-Abell J, Henderson J, Zheng P, Renvoisé B, Pang S, C Xu S, Saalfeld S et al..
2022. Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.. Human Molecular Genetics.