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1 Publications

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    Gonen Lab
    10/18/10 | An engineered DNA-binding protein self-assembles metallic nanostructures.
    Hall Sedlak R, Hnilova M, Gachelet E, Przybyla L, Dranow D, Gonen T, Sarikaya M, Tamerler C, Traxler B
    Chembiochem: A European Journal of Chemical Biology. 2010 Oct 18;11(15):2108-12. doi: 10.1002/cbic.201000407

    The golden age of DNA: We describe a strategy for engineering bifunctional proteins that simultaneously associate with metals and DNA to create self-assembled nanostructures. A DNA binding protein engineered with a gold binding peptide arranges colloidal gold particles along a DNA guide by virtue of its introduced peptide motif. These self-assembled complexes represent a step toward constructing nanoarchitectures with potential in nanoelectronic and photonic devices.

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