custom | custom
Filter
facetapi-Q2b17qCsTdECvJIqZJgYMaGsr8vANl1n | block
facetapi-PV5lg7xuz68EAY8eakJzrcmwtdGEnxR0 | block
Publication Date
facetapi-021SKYQnqXW6ODq5W5dPAFEDBaEJubhN | block
Type of Publication
- Remove Janelia filter Janelia
general_search_page-panel_pane_1 | views_panes
1 Publications
Showing 1-1 of 1 resultsYour Criteria:
Looger LabSchreiter Lab
07/01/08 |
Crystallization and preliminary x-ray characterization of the genetically encoded fluorescent calcium indicator protein GCaMP2.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 2008 Jul 1;64:629-31. doi: 10.1107/S1744309108016059
Fluorescent proteins and their engineered variants have played an important role in the study of biology. The genetically encoded calcium-indicator protein GCaMP2 comprises a circularly permuted fluorescent protein coupled to the calcium-binding protein calmodulin and a calmodulin target peptide, M13, derived from the intracellular calmodulin target myosin light-chain kinase and has been used to image calcium transients in vivo. To aid rational efforts to engineer improved variants of GCaMP2, this protein was crystallized in the calcium-saturated form. X-ray diffraction data were collected to 2.0 A resolution. The crystals belong to space group C2, with unit-cell parameters a = 126.1.