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    BAPTA-JF: Bright and Targetable Ca²⁺ Indicators
    Overview BAPTA-JF indicators merge the superior properties of the Janelia Fluor® dyes, the Ca²⁺ sensitivity of BAPTA, and the genetic targeting...
    Tools
    Biotin-Janelia Fluor® Conjugates
    Overview  Biotin-Janelia Fluor® conjugates are cell-permeable, fluorescent ligands designed for affinity purification using the HaloTag platform with easy confirmation using imaging. Drug-JF...
    Tools
    Bright, Photoactivatable (PA) Janelia Fluor® Dyes for Super-Resolution Imaging
    Overview Photoactivatable versions of Janelia Fluor® dyes combine the brightness and photostability of this small-molecule fluorophore platform with the spatial and temporal control of...
    Tools
    Dyes with a Universal Coumarin Switch for Super-Resolution Microscopy
    Overview A versatile platform enabling the construction of dyes for super-resolution imaging by coupling a coumarin auxiliary to rhodamine dyes. Dyes can be tuned to be either photochromic, with...
    Tools
    HaloCaMP: Chemigenetic Calcium Indicators Using HaloTag and Janelia Fluor Dyes
    Overview HaloCaMP integrates circularly permuted HaloTag proteins with a range of Janelia Fluor (JF) dyes to form...
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    Red-Shifted and Fluorinated Dyes "JF3" for Advanced Bioimaging
    Overview Fluorination and structural tuning of rhodamine scaffolds have yielded a powerful new class of bright, red-shifted fluorescent dyes for live-cell and super-resolution microscopy....
    Tools
    The Janelia Fluor® Dyes: Bright and Cell-Permeable Small-Molecule Fluorophores
    Overview The Janelia Fluor® dyes are a next-generation small-molecule fluorophore platform that combines superior brightness, photostability, and cell permeability with unprecedented modularity,...
    Tools
    The JFX™ Dyes
    Overview The JFX dye platform enhances the performance of Janelia Fluor® dyes by introducing deuterium at key positions, boosting brightness and extending photostability without altering their...
    Tools
    Vibratome built for the Auto Slicer Imager Rig (MouseLight 2)
    About the Innovation Visualization of the axonal structures of individual neurons is critical to understand how neural signals are organized and communicated in the brain. Janelia...