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Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Fly Facility
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2018
Liu J, Kline BA, Kenny TA, Smith DR, Soloveva V, Beitzel B, Pang S, Lockett S, Hess HF, Palacios G et al..
2018. A novel sheet-like virus particle array is a hallmark of Zika virus infection.. Emerging Microbes & Infections. 7(1):69.
2019
Hayworth KJ, Peale D, Januszewski M, Knott GW, Lu Z, C Xu S, Hess HF.
2019. Gas cluster ion beam SEM for imaging of large tissue samples with 10 nm isotropic resolution.. Nature Methods. 17(1):68-71.
Hayworth KJ, Peale DR, Januszewski M, Knott G, Lu Z, C. Xu S, Hess HF.
2019. GCIB-SEM: A path to 10 nm isotropic imaging of cubic millimeter volumes.. bioRxiv.
Ioannou MS, Jackson J, Sheu S-H, Chang C-L, Weigel AV, Liu H, H Pasolli A, C Xu S, Pang S, Matthies D et al..
2019. Neuron-astrocyte metabolic coupling protects against activity-induced fatty acid toxicity.. Cell. 177(6):1522-1535.e14.
Chang C-L, Weigel AV, Ioannou MS, H Pasolli A, C Xu S, Peale DR, Shtengel G, Freeman M, Hess HF, Blackstone C et al..
2019. Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III.. Journal of Cell Biology. 218(8):2583-99.
2020
García-Cerdán JG, Schmid EM, Takeuchi T, McRae I, McDonald KL, Yordduangjun N, Hassan AM, Grob P, C Xu S, Hess HF et al..
2020. Chloroplast Sec14-like 1 (CPSFL1) is essential for normal chloroplast development and affects carotenoid accumulation in Chlamydomonas.. Proceedings of the National Academy of Sciences of the U S A. 117(22):1-12.
Miron E, Oldenkamp R, Brown JM, Pinto DMS, C Xu S, Faria AR, Shaban HA, Rhodes JDP, Innocent C, de Ornellas S et al..
2020. Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin.. Science Advances. 6(39)
Scheffer LK, C Xu S, Januszewski M, Lu Z, Takemura S-ya, Hayworth KJ, Huang GB, Shinomiya K, Maitlin-Shepard J, Berg S et al..
2020. A connectome and analysis of the adult Drosophila central brain.. Elife. 9
Hoffman DP, Shtengel G, C Xu S, Campbell KR, Freeman M, Wang L, Milkie DE, H Pasolli A, Iyer N, Bogovic JA et al..
2020. Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells.. Science. 367(6475)
2021
Müller A, Schmidt D, C Xu S, Pang S, D'Costa JVerner, Kretschmar S, Münster C, Kurth T, Jug F, Weigert M et al..
2021. 3D FIB-SEM reconstruction of microtubule-organelle interaction in whole primary mouse β cells.. Journal of Cell Biology. 220(2)
Weigel AV, Chang C-L, Shtengel G, C Xu S, Hoffman DP, Freeman M, Iyer N, Aaron J, Khuon S, Bogovic J et al..
2021. ER-to-Golgi protein delivery through an interwoven, tubular network extending from ER.. Cell. 184(9):2412.
C Xu S, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura S-ya, Lu Z, H Pasolli A, Iyer N et al..
2021. An open-access volume electron microscopy atlas of whole cells and tissues.. Nature. 599(7883):147-51.
Heinrich L, Bennett D, Ackerman D, Park W, Bogovic J, Eckstein N, Petruncio A, Clements J, Pang S, C Xu S et al..
2021. Whole-cell organelle segmentation in volume electron microscopy.. Nature. 599(7883):141-46.
2022
Ritter AT, Shtengel G, C Xu S, Weigel A, Hoffman DP, Freeman M, Iyer N, Alivodej N, Ackerman D, Voskoboinik I et al..
2022. ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack.. Science. 376(6591):377-382.
Parlakgül G, Arruda APaula, Pang S, Cagampan E, Min N, Güney E, Lee GYankun, Inouye K, Hess HF, C Xu S et al..
2022. Regulation of liver subcellular architecture controls metabolic homeostasis.. Nature. 603(7902):736-742.
Zhu P-P, Hung H-F, Batchenkova N, Nixon-Abell J, Henderson J, Zheng P, Renvoisé B, Pang S, C Xu S, Saalfeld S et al..
2022. Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.. Human Molecular Genetics.
Zhu P-P, Hung H-F, Batchenkova N, Nixon-Abell J, Henderson J, Zheng P, Renvoisé B, Pang S, C Xu S, Saalfeld S et al..
2022. Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.. Human Molecular Genetics. 31(16):2779-2795.
2023
Zhu J, Boivin J-C, Pang S, C Xu S, Lu Z, Saalfeld S, Hess HF, Ohyama T.
2023. Comparative connectomics and escape behavior in larvae of closely related Drosophila species.. Current Biology.
2024
Obara CJ, Nixon-Abell J, Moore AS, Riccio F, Hoffman DP, Shtengel G, C Xu S, Schaefer K, H Pasolli A, Masson J-B et al..
2024. Motion of VAPB molecules reveals ER-mitochondria contact site subdomains.. Nature. 626(7997):169-176.