Conferences

This workshop will focus on the mechanisms and selective pressures driving the transition from unicellular to multicellular life, and the fundamental differences between them. Investigators working across a variety of model systems will address questions such as: What are the general principles of multicellularity, and what are the advantages and costs? How can theoretical models be applied to understanding of multicellular lifestyles? What new tools and approaches are needed to understand multicellular regulation?

This workshop will focus on the central role that theoretical frameworks and modeling play in understanding biological processes.  Theory and modeling have been a major source of insight and inspiration for experimental directions in all areas of biology; yet their full potential is untapped, and we seek principles that apply across diverse cellular and physiological systems.

This workshop will explore outstanding questions and challenges in the broad field of nutrition and metabolism. Metabolism operates at multiple length scales that are interconnected: metabolites, enzymes, metabolons, organelles, cells, organs, organisms, and their environments. Likewise, it is coupled to many processes, including genome regulation, signaling, growth, and development. The range of scales implies that multiple experimental and theoretical approaches are required to achieve a holistic picture of metabolism in action.

This workshop will focus on clinical and mechanistic paradigms in tissue repair. The capacity to restore cells and structures after injury differs dramatically across tissues and between species. Why can some tissues and organisms recreate structures virtually identical to what was lost, while others fail to repair at all, or seal the damage but remain functionally impaired? Our goal is to define key chokepoints, and forge new frontiers to ultimately advance regenerative medicine in humans.

We encourage applications from junior scientists pursuing research aimed at understanding how cognitive processes and behavior are implemented at the level of circuits, cells, and molecules. This meeting is open to a broad array of ideas and approaches in a variety of animal models. We will also consider theorists with a strong interest in linking their ideas to experimental data.

Organizers

Gwyneth Card, Janelia Research Campus/HHMI
Margaret Gardel, University of Chicago
Dan Goldman, Georgia Institute of Technology
Wyatt Korff, Janelia Research Campus/HHMI

Presentations and discussions in the symposium will focus on a variety of topics, including genetically encoded sensors for molecules or cellular states; light-, temperature-, or ligand-gated effectors of cell state; fluorescent proteins; labels for light or electron microscopy; tools for improving the performance and/or analysis of next-generation sequencing; viruses or other transgene delivery agents, and more.

Organizers

Luke Lavis, Janelia Research Campus/HHMI
Alison Tebo , Janelia Research Campus/HHMI
Jordan Meier, NCI/NIH