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9 ResultsShowing 1-9 of 9 results
CaMPARI (Calcium Modulated Photoactivatable Ratiometric Integrator) is a photoconvertible protein construct that enables imaging of the integrated calcium activity of large populations of cells...
Chimeric Ligand-Gated Ion Channels
In the nervous system, ligand-gated ion channels (LGICs) transduce chemical signals into electrical activity that communicates information. Implicated in many neurological disorders, LGICs are...
Current Iterations: GCaMP3, GCaMP5, GCaMP6 Fluorescent calcium indicators are an important tool used to detect and measure calcium, an essential regulator of cellular signaling. These...
Inventors at Janelia have developed a strategy for the creation of genetically encoded, intensity-based fluorescent sensors and an associated unique set of analytical tools that can measure...
The major neurotransmitter in the brain, glutamate is an important signaling molecule in biological organisms. The ability to visualize and quantitate glutamate transients is broadly useful to...
mEos2 & mEos4
A new photo-convertible fluorescent protein for use in fluorescence microscopy, mEos4, has been developed by researchers at the Howard Hughes Medical Institute’s Janelia Farm Research Campus...
rAAV2-retro: Efficient retrograde access to projection neurons for gene delivery
Scientists at the Howard Hughes Medical Institute’s Janelia Research Campus and University of California, Berkeley have developed a powerful new potential delivery and targeting system for...
Related: see the description of jRCaMP1 here. A family of genetically encoded calcium indicators (GECIs) from fluorescent proteins other than Aquorea...
Single-Fluorescent Protein Biosensors
Maltose Sensor - Glutamate Sensor - Phosphonate Sensor Inventors at Howard Hughes Medical Center’s Janelia Research Campus have produced a general strategy for the creation of...